It is possibly still the most famous fixture in Bournemouth's history and always brings back memories of their FA Cup upset in 1984 when being a then division three side knocked out the cup holders at Dean Court.
A lot has changed since then with United going on to be one of the worlds biggest clubs and the Cherries going through the leagues to join them at footballs elite table.
Since their arrival, they have become an established Premier League club but this season could be the one where they lose their place.
Currently 19th with 27 points they are a point away from safety with a struggle taking place with four other clubs in the frame with Norwich looking doomed.
Since the restart, they have failed to pick up a point and with four games against top-eight clubs coming up points are needed soon.
United, on the other hand, can do no wrong, 15 unbeaten since their home defeat to Burnley and they’ve clawed their way back into Champions League contention with eyes on 3rd place and still with FA Cup and Europa League hopes of a trophy to end the season.
United have no new injury worries with only Phil Jones still out but manager Solksjaer saying he may make changes to keep players fresh.
Bournemouth will be without striker Callum Wilson after he picked up his 10th booking of the season against Wolves, Charlie Daniels is set to miss the match with a long term knee injury although Josh King should be fit after getting through 90 minutes unscathed against Newcastle.
This has all the look of a one-sided game and I can see the cherries being ripe for the picking, so I'm predicting a 4-0 win for the Red Devils.
Match Preview written by Graham Ives.